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A girl smiles, standing outside on grass. It is sunny and there are trees behind her. She holds a water bottle in one hand and a small pill in the other.
Eyrusalem, one of the millions of people who took Zithromax, an antibiotics that treats blinding trachoma.

Neglected Tropical Eye Diseases

Neglected tropical diseases (NTDs) affect more than one billion people globally. Predominantly found in lower-income regions and conflict areas, people affected by them are often trapped by a cycle of poverty and disease.

  • Neglected tropical diseases are endemic in almost 150 countries. However, the majority of the NTD burden is concentrated in low- and middle-income countries in Africa, Asia, and Latin America.
  • More than 1 billion people – one-sixth of the world’s population – are infected with one or more NTDs, and an additional two billion are at risk. Each year, about 185,000 people die as a result of NTDs.
  • Infection with an NTD may result in severe disability, disfigurement, blindness, and malnutrition. Also, individuals are often infected with multiple NTDs simultaneously. Globally more than 47.9 million disabilities are caused due to NTDs.
  • The average trachoma infection rate in Ethiopia is around 26.9%.
  • The end of NTDs is expected to result in an estimated net benefit to affected individuals of about US$ 25 for every US$ 1 invested in preventive therapy.

Together with our partners, we fight three of these NTDs: trachoma, river blindness and lymphatic filariasis. Focusing especially on preventive treatment, we limit their spread through:

  • raising awareness and providing clean water and sanitation facilities
  • providing medicines
  • case detection, case management and improved vector control

Effects of tropical diseases

There are three people in the image, sitting in front of a wall. The boy is on the left, wearing a bandage over his eye, with his family on the right. They are all smiling.
Mohamed Ahemed sits with his grandfather and his mother, after receiving surgery for Trachomatous Trichiasis (TT – a neglected tropical disease). © Genaye Eshetu / Light for the World

Trachoma

Trachoma is the world’s leading infectious cause of blindness. It is a bacterial infection of the eye affecting an estimated 1.9 million people worldwide. Trachoma occurs primarily among children and is transmitted through human contact and flies. It is especially prevalent in poorer communities. If detected early, medication and surgery can help, but if untreated, the disease leads to blindness via trichiasis.

A young Ethiopian girl takes medication as part of the first child MDA against trachoma in Tigray.
A young girl receives medicine as part of the first MDA in Tigray. © Ephrem Taye/Light for the World.

Onchocerciasis (River Blindness)

Onchocerciasis, or River Blindness, is caused by infection with a parasitic worm transmitted by the blackfly species. It mainly affects communities living near rivers where blackfly species live and breed. River blindness is the second most common infectious cause of blindness.

Haile Tesfaye, 32, waits for his trichiasis surgery at Quiha Hospital Secondary Eye Care Unit, Tigray region, Ethiopia.

Lymphatic Filariasis (Elephantiasis)

Lymphatic filariasis is caused by infection with parasitic worms transmitted by mosquitoes. The parasites settle in the lymphatic system, disrupting the drainage of lymphatic fluid and causing permanent inflammation and bloating of the limbs.